St. John’s Wort.
St John’s Wort (Hypericum Perforatum) is a perennial flowering plant widely known for its
antidepressant qualities. St. John’s Wort is used extensively by
European physicians in the treatment of mild to moderate
depression.
Since approximately 18 million Americans suffer from depression in
a given year from many different causes, St. John’s Wort is
attracting attention as a safe alternative to the prescription
medications that are being prescribed now.
Two compounds, hypericin and hyperforin, give St. John’s Wort its
ability to support moods and counteract feelings of depression.
St. John’s Wort also contains various flavonoids and
proanthoclanidin polymers. These compounds inhibit the breakdown
of neurotransmitters, including serotonin.
St. John Wort specifically inhibits the enzyme,
catechol-O-methyltransferase which is known to degrade certain
neurotransmitters like dopamine. St. John’s Wort is also known to
reduce the expression of interlevkin-6 and gamma-amino-butyric
acid (GABA) uptake. These actions contribute to alleviating
depression by slowing the recycling process of neurotransmitters
needed for maintaining emotional balance.
Saint John’s Wort has been shown to help:
_ Relieve mild to moderate depression. It also aids in the
treatment of SAD, or seasonal affective disorder, which is a type
of depression that is linked to the shortage of daylight in the
winter and fall.
_ Control certain PMS (Premenstrual Syndrome) and fibromyalgia
symptoms.
_ Ease anxiety, stress and chronic pain.
_ Ward off infections.
_ Increase energy levels.
_ Control appetite and promote weight loss.
_ Improve sleep patterns in older people.
_ Inhibit the replication of several viruses, including HIV, the
herpes complex and the virus that causes mononucleosis.
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