Zyban, Zyban SR Information.
The following information is intended to supplement, not
substitute, the expertise and judgment of your physician,
pharmacist or other healthcare professional. It should not be
construed to indicate that using Zyban SR is safe or appropriate
for you.
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information and side effects before deciding to take Zyban.
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What is Zyban used for? Bupropion is an antidepressant of
the aminoketone class that is chemically unrelated to tricyclic,
selective serotonin re-uptake inhibitor or other antidepressants.
The brand name Wellbutrin is used to
treat depression while the brand name Zyban SR is used as a
smoking cessation aid.
General Zyban Precautions:
_ Zyban SR can be habit forming.
_ Talk to your doctor about alcohol use before starting treatment
with Zyban SR. Alcohol may increase the risk of having a seizure
while taking bupropion. Avoid alcohol or drink it only in
moderation while taking Zyban.
_ Never take more Zyban than is directed by your doctor. Higher
doses of bupropion may increase the risk of a seizure.
_ Zyban SR may cause dizziness. If you experience dizziness, avoid
driving, operating machinery, or performing other hazardous
activities.
_ Rise slowly when rising from a sitting or lying position to
prevent dizziness or possible falls.
_ Do not take Zyban SR if you have taken a monoamine oxidase
inhibitor (MAOI) within the last 14 days. A dangerous drug
interaction can occur if bupropion is combined with MAO
inhibitors.
_ It is not known whether Zyban will harm an unborn or nursing
baby. Do not take Zyban if you are pregnant or could become
pregnant without first talking to your doctor.
_ Tell the doctor or dentist that you are taking Zyban if you are
having surgery, including dental surgery.
_ Zyban SR may impair judgment, thinking, or motor skills.
Patients using bupropion should exercise caution until they have
adapted to therapy.
_ If you skip the missed dose and take only the next one as
directed. Do not take a double dose of Zyban. Overdose is
possible.
_ Too much bupropion can increase the risk of a seizure. Do not be
taking more than one product containing bupropion at a time (Wellbutrin
and Zyban SR).
_ Zyban SR and a nicotine replacement product together may raise
blood pressure. Nicotine replacement products can be used during
treatment with Zyban SR under the supervision of a doctor.
_ Do not smoke at any time if using a nicotine product with Zyban
SR.
FDA Warnings for bupropion: The FDA issued a public health
alert in March 2004 warning that bupropion can lead to deeper
depression and suicide. The FDA recommends that health care
providers warn patients, their families and their caregivers to be
alert for agitation, irritability, suicide and worsening
depression while using bupropion. The FDA also recommends that
health care providers closely monitor adult and children treated
with bupropion for worsening of depression or suicidal tendencies,
especially at the beginning of therapy or when the dose either
increases or decreases.
Zyban SR can cause serious side
effects. Only you can decide if Zyban is best for you. It is
important for people currently taking Zyban to discuss side effect
concerns with their physician.
Zyban Side Effects:
_ Seizures.
_ Rapid or irregular heartbeats.
_ Chest pain.
_ Change in sex drive or ability.
_ Impotence.
_ Loss of libido.
_ Difficulty urinating or frequent urination.
_ Shortness of breath.
_ Headache.
_ Insomnia or sleeplessness.
_ Nightmares.
_ Dry mouth.
_ Drowsiness.
_ Restlessness.
_ Dizziness.
_ Weight gain or weight loss.
_ Weakness.
_ Anxiety.
_ Agitation.
_ Tremors.
_ Excessive sweating.
_ Skin rash.
_ Itching.
_ Hives.
_ Blurred vision.
_ Loss of coordination.
_ Muscle or joint pain.
_ Ringing in the ears.
_ Flu-like symptoms such as aching muscles, fatigue, and
discomfort.
_ Fever.
_ Constipation.
Contact your doctor immediately if you experience: An
allergic reaction (difficulty breathing; closing of the throat;
swelling of the lips, face, or tongue; or hives). Stop taking
Zyban and contact your doctor immediately or seek emergency
medical treatment if you also experience a fast or irregular
heartbeat or seizures. Contact your doctor immediately if you
experience yellowing of the skin or eyes.
Before taking Zyban, tell your doctor if you have or ever had:
_ Seizures or epilepsy.
_ Head injury or brain or spinal column tumor.
_ Diabetes.
_ Liver disease.
_ Kidney disease.
_ Heart disease.
_ High blood pressure.
_ History of heart attack.
_ Suicidal thoughts.
_ Anorexia, bulimia or other eating disorders.
_ Drink alcohol.
_ Use street drugs or take a prescription benzodiazepine such as
Xanax, Valium or Restoril.
_ Glaucoma.
_ Enlarged prostate.
_ Difficulty urinating.
_ An overactive thyroid gland.
What should I avoid while taking Zyban?
_ Alcohol may increase the risk of having a seizure while taking
Zyban. Avoid alcohol or drink it only in moderation while taking
Zyban.
_ Never take more Zyban than is directed by your doctor. Higher
doses of bupropion may increase the risk of a seizure.
Symptoms of overdose may include: Symptoms of a Zyban
overdose include seizures, loss of consciousness, weakness,
hallucinations, rapid or irregular heartbeat, heart attack,
difficulty breathing or swallowing, dizziness, fainting, confusion
and blurred vision.
What other drugs will affect bupropion? Zyban can increase
the effects of many other drugs, leading to serious side effects.
If taking Zyban, talk to your doctor and pharmacist before taking
any prescription or over-the-counter medicines. Do not take
bupropion with the following medicines without your doctor’s
approval:
_ Other bupropion products.
_ Carbamazepine
_ Cimetidine.
_ Insulin.
_ Levodopa.
_ Lithium.
_ MAO inhibitors.
_ Other antidepressants.
_ Methylphenidate.
_ Ritonavir.
_ Theophylline.
Zyban can also interfere with anticoagulants, antihistamines,
antipsychotics, diet pills, medication for high blood pressure,
seizures, asthma, colds, or allergies; oral anti-diabetic
medications, sedatives, sleeping pills, thyroid medications,
tranquilizers, and vitamins. Drugs other than the above listed may
also interact with Zyban. Talk to your doctor and pharmacist
before taking any prescription, over-the-counter medicines or
natural supplements.
People should carefully evaluate Zyban information and side
effects before deciding to take Zyban. Consult your healthcare
professional before using Zyban.
*This antidepressant drug
information does not endorse Zyban, diagnose patients or
recommend therapy. The information contained herein is not
intended to cover all possible warnings, uses, precautions, drug
interactions, allergic reactions, or adverse side effects of Zyban.
If you have questions about the drugs you are taking, check with
your health care provider or pharmacist. The information provided
should not be construed to indicate that Zyban is safe, effective
or appropriate.
Do not stop taking Zyban without first talking to your doctor.
Your doctor may need to gradually reduce the dose before stopping
Zyban completely. Suddenly stopping bupropion may cause unpleasant
and potentially serious side effects.
